Scientists at the Brain Networks Laboratory of Texas A&M University have developed a machine that slices a mammalian brain into micrometer pieces and scans its three-dimensional images to assemble them into maps.
The knife-edge scanning microscope (KESM) uses a diamond knife for slicing of the tissues and once it is done with this operation with a microscope the images are scanned at 300nm. Let’s say, in order to scan the full brain of a mouse this automated machines requires little over four days.
The images produced by this system can be assembled together to create a web-based 3D map of brains, which is powered by Google Maps API.
The team of researchers has created an atlas of mouse brains to help potential doctors, or others, best understand and study these to advance into human genetics.